[2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane

Base Information

• Chemical Name: [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane
• CAS No.: 206259-63-4
• Molecular Formula: C₄₅H₆₀Br₂O₅Si
• Molecular Weight: 868.862
• Mol file: 206259-63-4.mol

Synonyms:[2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane

Chemical Property of [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane

There total 4 articles about [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,3-dibromo-propane (109-64-8) + C39H50O5Si (206259-62-3) → [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane (206259-63-4)

Guidance literature:

With potassium carbonate; In acetone;

DOI:10.1021/jo9619600

Reference yield:

4-(2-(4-(benzyloxy)phenyl)propan-2-yl)phenol (42781-88-4) → [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane (206259-63-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 89 percent / NaH / dimethylformamide

2: imidazole / dimethylformamide

3: H₂ / Pd/C / tetrahydrofuran

4: 100 percent / K₂CO₃ / acetone

With 1H-imidazole; hydrogen; sodium hydride; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; N,N-dimethyl-formamide; acetone; 1: Etherification / 2: silylation / 3: Hydrogenolysis / 4: Etherification;

DOI:10.1021/jo9619600

Reference yield:

1,3-bis-{4-[1-(4-benzyloxy-phenyl)-1-methyl-ethyl]-phenoxy}-propan-2-ol (206259-61-2) → [2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane (206259-63-4)

Guidance literature:

Multi-step reaction with 3 steps

1: imidazole / dimethylformamide

2: H₂ / Pd/C / tetrahydrofuran

3: 100 percent / K₂CO₃ / acetone

With 1H-imidazole; hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; N,N-dimethyl-formamide; acetone; 1: silylation / 2: Hydrogenolysis / 3: Etherification;

DOI:10.1021/jo9619600

upstream raw materials:

1,3-dibromo-propane

C₃₉H₅₀O₅Si

4-(2-(4-(benzyloxy)phenyl)propan-2-yl)phenol

1,3-bis-{4-[1-(4-benzyloxy-phenyl)-1-methyl-ethyl]-phenoxy}-propan-2-ol