(1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

Base Information

Chemical Name:(1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate
CAS No.:623562-38-9
Molecular Formula:C₂₀H₂₉NO₃
Molecular Weight:331.455
Hs Code.:

Synonyms:(1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

Chemical Property:

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Technology Process of (1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

There total 2 articles about (1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33744-74-0
menthyl hydrogen phthalate

: 623562-38-9
(1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 2.75 g / Et₃N / diethyl ether / 1.5 h / 20 °C / Heating

2: 5.44 g / Et₃N / 2 h

With triethylamine; In diethyl ether;
DOI:10.1002/hlca.200390236

Reference yield:

: 557-66-4
ethanamine hydrochloride

: 2-Ethoxycarbonyloxycarbonyl-benzoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

: 623562-38-9
(1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

Guidance literature:: With triethylamine; for 2h;
DOI:10.1002/hlca.200390236

Reference yield:

: 623562-38-9
(1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-[(ethylamino)carbonyl]benzoate

: 2216-51-5
(-)-menthol

Guidance literature:: With phosphate buffer; borate buffer; In water; acetonitrile; at 20 ℃; pH=7.62; Further Variations:; pH-values; Reagents; Kinetics;
DOI:10.1002/hlca.200390236