3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate

Base Information

• Chemical Name: 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate
• CAS No.: 119944-30-8
• Molecular Formula: C₂₆H₄₆O₅S
• Molecular Weight: 470.714
• Mol file: 119944-30-8.mol

Synonyms:3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate

Chemical Property of 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate

There total 4 articles about 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-Hexadecanol (36653-82-4,124-29-8) + (S)-Glycidyl tosylate (70987-78-9,6746-81-2) → 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate (119944-30-8)

Guidance literature:

boron trifluoride diethyl etherate; In chloroform;

DOI:10.1016/S0040-4039(00)80503-1

Reference yield: 60.0%

(R)-3-(hexadecyloxy)-1,2-propanediol (10550-58-0) + p-toluenesulfonyl chloride (98-59-9) → 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate (119944-30-8)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 23 ℃; for 4h;

DOI:10.3390/molecules25030566

Reference yield:

1-Hexadecanol (36653-82-4,124-29-8) + (S)-Glycidyl tosylate (70987-78-9,6746-81-2) → 3-hexadecyloxy-2R-hydroxypropyl 1-para-toluenesulphonate (120019-37-6) + 3‐hexadecyloxy‐2R‐hydroxyl propyl‐1‐p‐toluene sulphonate (119944-30-8)

Guidance literature:

boron trifluoride diethyl etherate; In chloroform; for 18h; Yield given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/ja00190a059

upstream raw materials:

1-Hexadecanol

(S)-Glycidyl tosylate

(R)-glycidyl tosylate

(R)-3-(hexadecyloxy)-1,2-propanediol

Downstream raw materials:

3-O-hexadecyl-2-O-palmitoyl-sn-glycerol 1-p-toluenesulfonate

(-)-1-O-hexadecyl-2-O-methyl-sn-glycerol

(R)-2-benzyloxy-3-hexadecyloxy-propan-1-ol

3-O-hexadecyl-2-lyso-sn-glycero-1-phosphocholine