Technology Process of (5R,6R)-5-acetoxy-6-(benzyloxy)hexadecanoic acid
There total 9 articles about (5R,6R)-5-acetoxy-6-(benzyloxy)hexadecanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium chlorite; potassium dihydrogenphosphate; 2-methyl-but-2-ene;
In
water; tert-butyl alcohol;
for 0.5h;
Ambient temperature;
DOI:10.1021/jo00376a056
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 92 percent / sodium hydride / tetrahydrofuran / 10 h / Heating
2: 82 percent / N-chlorossucinimide, sodium bicarbonate, silver nitrate / acetone; H2O / 0.17 h / Ambient temperature
3: diethyl ether / 1 h / -78 °C
4: 93 percent / 4-dimethylaminopyridine / Ambient temperature
5: 1.) ozone, 2.) dimethyl sulfide / 1.) CH2Cl2, -78 deg C, 2.) CH2Cl2, RT, 1 h
6: 96 percent / 2-methyl-2-butene, sodium chlorite, KH2PO4 / 2-methyl-propan-2-ol; H2O / 0.5 h / Ambient temperature
With
dmap; sodium chlorite; potassium dihydrogenphosphate; N-chloro-succinimide; 2-methyl-but-2-ene; dimethylsulfide; sodium hydride; sodium hydrogencarbonate; ozone; silver nitrate;
In
tetrahydrofuran; diethyl ether; water; acetone; tert-butyl alcohol;
DOI:10.1021/jo00376a056
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diethyl ether / 1 h / -78 °C
2: 93 percent / 4-dimethylaminopyridine / Ambient temperature
3: 1.) ozone, 2.) dimethyl sulfide / 1.) CH2Cl2, -78 deg C, 2.) CH2Cl2, RT, 1 h
4: 96 percent / 2-methyl-2-butene, sodium chlorite, KH2PO4 / 2-methyl-propan-2-ol; H2O / 0.5 h / Ambient temperature
With
dmap; sodium chlorite; potassium dihydrogenphosphate; 2-methyl-but-2-ene; dimethylsulfide; ozone;
In
diethyl ether; water; tert-butyl alcohol;
DOI:10.1021/jo00376a056
