ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

Base Information

Chemical Name:ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride
CAS No.:1366063-16-2
Molecular Formula:C₁₅H₁₇F₃N₂O₃*ClH
Molecular Weight:366.768
Hs Code.:

Synonyms:ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

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Chemical Property of ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

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Technology Process of ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

There total 3 articles about ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1366062-82-9
ethyl 1-({[(tert-butoxycarbonyl)amino][3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate

: 1366063-16-2
ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 146621-92-3
2-{[(tert-butoxy)carbonyl]amino}-2-[3-(trifluoromethyl)phenyl]acetic acid

: 1366063-16-2
ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C

2: hydrogenchloride / 1,4-dioxane; dichloromethane / 3 h / 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 72784-47-5
ethyl 1-aminocyclopropane-1-carboxylate

: 1366063-16-2
ethyl 1-({amino[3-(trifluoromethyl)phenyl]acetyl}amino)cyclopropanecarboxylate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C

2: hydrogenchloride / 1,4-dioxane; dichloromethane / 3 h / 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;