4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine

Base Information

• Chemical Name: 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine
• CAS No.: 138536-85-3
• Molecular Formula: C₁₉H₂₃NO₂
• Molecular Weight: 297.397
• Mol file: 138536-85-3.mol

Synonyms:4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine

Chemical Property of 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine

There total 4 articles about 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4'-(5,5-Dimethyl-[1,3]dioxan-2-yl)-biphenyl-4-carbaldehyde oxime (138536-84-2) → 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine (138536-85-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 70 ℃; for 6h;

DOI:10.1246/bcsj.64.3005

Reference yield:

4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-carbaldehyde (138536-74-0) → 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine (138536-85-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / hydroxylamine hydrochloride, sodium carbonate / ethanol; CH₂Cl₂; H₂O / Ambient temperature

2: 81 percent / LiAlH₄ / tetrahydrofuran / 6 h / 70 °C

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium carbonate; In tetrahydrofuran; ethanol; dichloromethane; water;

DOI:10.1246/bcsj.64.3005

Reference yield:

[4'-(5,5-Dimethyl-[1,3]dioxan-2-yl)-biphenyl-4-yl]-methanol (152424-50-5) → 4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-methanamine (138536-85-3)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridinium chlorochromate, sodium acetate

2: 74 percent / hydroxylamine hydrochloride, sodium carbonate / ethanol; CH₂Cl₂; H₂O / Ambient temperature

3: 81 percent / LiAlH₄ / tetrahydrofuran / 6 h / 70 °C

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium acetate; sodium carbonate; pyridinium chlorochromate; In tetrahydrofuran; ethanol; dichloromethane; water;

DOI:10.1246/bcsj.64.3005

upstream raw materials:

4'-(5,5-Dimethyl-[1,3]dioxan-2-yl)-biphenyl-4-carbaldehyde oxime

4'-(5,5-dimethyl-1,3-dioxan-2-yl)-<1,1'-biphenyl>-4-carbaldehyde

[4'-(5,5-Dimethyl-[1,3]dioxan-2-yl)-biphenyl-4-yl]-methanol

2,2-Dimethyl-1,3-propanediol

Downstream raw materials:

N-hexyl-N'-<<4'-formyl-<1,1'-biphenyl>-4-yl>methyl>-1,2:4,5-benzenebis(dicarboximide)

2-Hexyl-6-[4'-((1Z,4Z,9Z,15Z)-2,8,12,18-tetrahexyl-3,7,13,17-tetramethyl-15-p-tolyl-porphyrin-5-yl)-biphenyl-4-ylmethyl]-pyrrolo[3,4-f]isoindole-1,3,5,7-tetraone