N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Base Information

Chemical Name:N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine
CAS No.:110143-44-7
Molecular Formula:C₃₆H₄₇NO₄Si
Molecular Weight:585.859
Hs Code.:

Synonyms:N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Suppliers and Price of N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

There total 7 articles about N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 93-97-0
benzoic acid anhydride

: 110143-44-7
N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Guidance literature:: Multi-step reaction with 7 steps

1: 84 percent / Et₃N / CH₂Cl₂ / Ambient temperature

2: 99 percent / benzene / 7 h / Heating

3: 64 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Heating

4: 1.) KH, 2.) n-BuLi

5: 99 percent / oxalyl chloride, DMSO / CH₂Cl₂ / 1 h / -78 - -40 °C

6: 99 percent / tetrahydrofuran / 48 h / Ambient temperature

7: potassium hydride / tetrahydrofuran / 22 h / Ambient temperature

With lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; potassium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; benzene;
DOI:10.1021/jm00394a016

Reference yield:

: 7679-18-7
N-desmethylthebaine hydrochloride

: 110143-44-7
N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Guidance literature:: Multi-step reaction with 7 steps

1: 84 percent / Et₃N / CH₂Cl₂ / Ambient temperature

2: 99 percent / benzene / 7 h / Heating

3: 64 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Heating

4: 1.) KH, 2.) n-BuLi

5: 99 percent / oxalyl chloride, DMSO / CH₂Cl₂ / 1 h / -78 - -40 °C

6: 99 percent / tetrahydrofuran / 48 h / Ambient temperature

7: potassium hydride / tetrahydrofuran / 22 h / Ambient temperature

With lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; potassium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; benzene;
DOI:10.1021/jm00394a016

Reference yield:

: 110173-64-3
N-benzoylnorthebaine maleic anhydride adduct

: 110143-44-7
N-benzyl-7α-vinyl-8α-<<(tert-butyldimethylsilyl)oxy>methyl>-endo-ethylenetetrahydronorthebaine

Guidance literature:: Multi-step reaction with 5 steps

1: 64 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Heating

2: 1.) KH, 2.) n-BuLi

3: 99 percent / oxalyl chloride, DMSO / CH₂Cl₂ / 1 h / -78 - -40 °C

4: 99 percent / tetrahydrofuran / 48 h / Ambient temperature

5: potassium hydride / tetrahydrofuran / 22 h / Ambient temperature

With lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; potassium hydride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00394a016