trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide

Base Information

• Chemical Name: trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide
• CAS No.: 1426658-31-2
• Molecular Formula: C₂₀H₁₈F₁₇N₂O₃S*I
• Molecular Weight: 816.318
• Mol file: 1426658-31-2.mol

Synonyms:trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide

Chemical Property of trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide

There total 4 articles about trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-(2-dimethylamino-ethyl)-4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoro-methyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonamide (1426658-29-8) + methyl iodide (74-88-4) → trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide (1426658-31-2)

Guidance literature:

In acetonitrile; for 5h; Reflux; Inert atmosphere;

DOI:10.1016/j.jfluchem.2013.08.007

Reference yield:

perfluoro(4-methyl-3-isopropyl-2-pentene) (30320-27-5) → trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide (1426658-31-2)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium carbonate / dimethyl sulfoxide / 6 h / 20 - 75 °C

2: chlorosulfonic acid / dichloromethane / 3 h / 20 °C / Reflux

3: potassium carbonate / acetonitrile / 5 h / 20 °C / Reflux

4: acetonitrile / 5 h / Reflux; Inert atmosphere

With chlorosulfonic acid; sodium carbonate; potassium carbonate; In dichloromethane; dimethyl sulfoxide; acetonitrile;

DOI:10.1016/j.jfluchem.2013.08.007

Reference yield:

[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene (66432-85-7) → trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide (1426658-31-2)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorosulfonic acid / dichloromethane / 3 h / 20 °C / Reflux

2: potassium carbonate / acetonitrile / 5 h / 20 °C / Reflux

3: acetonitrile / 5 h / Reflux; Inert atmosphere

With chlorosulfonic acid; potassium carbonate; In dichloromethane; acetonitrile;

DOI:10.1016/j.jfluchem.2013.08.007

upstream raw materials:

perfluoro(4-methyl-3-isopropyl-2-pentene)

[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene

N-(2-dimethylamino-ethyl)-4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoro-methyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonamide

methyl iodide