[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene

Base Information

• Chemical Name: [3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene
• CAS No.: 66432-85-7
• Molecular Formula: C₁₅H₅F₁₇O
• Molecular Weight: 524.177
• Mol file: 66432-85-7.mol

Synonyms:[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene

Chemical Property of [3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene

There total 1 articles about [3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

perfluoro(4-methyl-3-isopropyl-2-pentene) (30320-27-5) + phenol (108-95-2,27073-41-2) → [3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene (66432-85-7)

Guidance literature:

With sodium carbonate; In dimethyl sulfoxide; at 20 - 75 ℃; for 6h;

DOI:10.1016/j.jfluchem.2013.08.007

Reference yield: 88.0%

[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene (66432-85-7) → 4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-tri-fluoromethyl-but-1-enyloxy]-benzenesulfonyl chloride (903631-13-0)

Guidance literature:

With chlorosulfonic acid; In dichloromethane; at 20 ℃; for 3h; Reflux;

DOI:10.1016/j.jfluchem.2013.08.007

Reference yield:

[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoro-methyl-but-1-enyloxy]-benzene (66432-85-7) → N-(2-dimethylamino-ethyl)-4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoro-methyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonamide (1426658-29-8)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfonic acid / dichloromethane / 3 h / 20 °C / Reflux

2: potassium carbonate / acetonitrile / 5 h / 20 °C / Reflux

With chlorosulfonic acid; potassium carbonate; In dichloromethane; acetonitrile;

DOI:10.1016/j.jfluchem.2013.08.007

upstream raw materials:

perfluoro(4-methyl-3-isopropyl-2-pentene)

phenol

Downstream raw materials:

4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-1,3-bis-tri-fluoromethyl-but-1-enyloxy]-benzenesulfonyl chloride

N-(2-dimethylamino-ethyl)-4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoro-methyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonamide

trimethyl-(2-{4-[3,4,4,4-tetrafluoro-2-(1,2,2,2-tetra-fluoro-1-trifluoromethyl-ethyl)-1,3-bis-trifluoromethyl-but-1-enyloxy]-benzenesulfonylamino}-ethyl)-ammonium iodide