N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

Base Information

Chemical Name:N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide
CAS No.:1071927-06-4
Molecular Formula:C₂₁H₁₉Cl₂F₃N₂O₂
Molecular Weight:459.295
Hs Code.:

Synonyms:N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

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Chemical Property of N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

Chemical Property:

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Technology Process of N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

There total 4 articles about N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1070396-59-6
3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]aniline

: 3282-30-2
pivaloyl chloride

: 1071927-06-4
N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield:

: 1070396-55-2
3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]nitrobenzene

: 1071927-06-4
N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / iron / ethanol; water / 1.25 h / 75 °C

2: triethylamine / tetrahydrofuran / 1 h / 20 °C

With acetic acid; triethylamine; iron; In tetrahydrofuran; ethanol; water;

Reference yield:

: 3431-62-7,20747-39-1
3-nitrobenzaldoxime

: 1071927-06-4
N-(3-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-trifluoromethyl-isoxazol-3-yl)phenyl)pivaloylamide

Guidance literature:: Multi-step reaction with 4 steps

1: N-chloro-succinimide / N,N-dimethyl-formamide / 1 h / 20 - 60 °C

2: triethylamine / N,N-dimethyl-formamide / 6 h / 20 °C

3: acetic acid / iron / ethanol; water / 1.25 h / 75 °C

4: triethylamine / tetrahydrofuran / 1 h / 20 °C

With N-chloro-succinimide; acetic acid; triethylamine; iron; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;