1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Base Information

Chemical Name:1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol
CAS No.:434300-61-5
Molecular Formula:C₄₄H₄₆O₁₁S
Molecular Weight:782.909
Hs Code.:

Synonyms:1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Suppliers and Price of 1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

There total 13 articles about 1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 124-63-0
methanesulfonyl chloride

: 434300-60-4
1L-1-O-bezoyl-3,6-di-O-benzyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

: 434300-61-5
1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Guidance literature:: With pyridine; at 20 ℃; for 7h;
DOI:10.1021/jo010925c

Reference yield:

: (±)-1,2:4,5-di-O-cyclohexylidene-myo-inositol

: 434300-61-5
1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Guidance literature:: Multi-step reaction with 8 steps

1.1: NaH / dimethylformamide / 1.5 h / 0 - 20 °C

1.2: 84 percent / dimethylformamide / 3.5 h / 0 - 20 °C

2.1: 74 percent / p-TsOH*H₂O; ethanol / 2 h / 45 °C

3.1: NaH / tetrahydrofuran / 1.5 h / 0 - 20 °C

3.2: nBu₄NI / tetrahydrofuran; dimethylformamide / 12 h / 20 °C

4.1: 13.2 g / AcOH; water / 1 h / 50 °C

5.1: 41 percent / 4-dimethylaminopyridine; 1,3-dicyclohexylcarbodiimide / CH₂Cl₂ / 3.5 h / -15 °C

6.1: 81 percent / NaOMe / methanol / 0.5 h / 20 °C

7.1: 84 percent / pyridine / 12 h / 20 °C

8.1: 97 percent / pyridine / 7 h / 20 °C

With pyridine; dmap; ethanol; water; sodium methylate; sodium hydride; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo010925c

Reference yield:

: (±)-1,4-di-O-benzyl-2,3:5,6-di-O-cyclohexylidene-myo-inositol

: 434300-61-5
1L-1-O-benzoyl-3,6-di-O-benzyl-2-O-methanesulfonyl-4,5-di-O-(p-methoxybenzyl)-myo-inositol

Guidance literature:: Multi-step reaction with 7 steps

1.1: 74 percent / p-TsOH*H₂O; ethanol / 2 h / 45 °C

2.1: NaH / tetrahydrofuran / 1.5 h / 0 - 20 °C

2.2: nBu₄NI / tetrahydrofuran; dimethylformamide / 12 h / 20 °C

3.1: 13.2 g / AcOH; water / 1 h / 50 °C

4.1: 41 percent / 4-dimethylaminopyridine; 1,3-dicyclohexylcarbodiimide / CH₂Cl₂ / 3.5 h / -15 °C

5.1: 81 percent / NaOMe / methanol / 0.5 h / 20 °C

6.1: 84 percent / pyridine / 12 h / 20 °C

7.1: 97 percent / pyridine / 7 h / 20 °C

With pyridine; dmap; ethanol; water; sodium methylate; sodium hydride; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo010925c