1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

Base Information

Chemical Name:1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea
CAS No.:864244-86-0
Molecular Formula:C₂₀H₁₆F₂N₄O₂S
Molecular Weight:414.435
Hs Code.:

Synonyms:1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

Suppliers and Price of 1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

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Technology Process of 1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

There total 2 articles about 1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 864248-45-3
(4-fluorophenyl)acetyl isothiocyanate

: 864244-74-6
4-(4-amino-2-fluorophenoxy)pyridin-2-amine

: 864244-86-0
1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

Guidance literature:: In dichloromethane; ethyl acetate; at 20 ℃; for 20h;

Reference yield:

: 864244-74-6
4-(4-amino-2-fluorophenoxy)pyridin-2-amine

: 333-20-0
potassium thioacyanate

: 864244-86-0
1-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thiourea

Guidance literature:: potassium thioacyanate; 4-Fluorophenylacetyl chloride; In acetonitrile; at 50 ℃; for 1h;

4-(4-amino-2-fluorophenoxy)pyridin-2-amine; In acetonitrile; at 20 ℃; for 59.5h;