1,3-diphenylpropan-1-ol

Base Information

• Chemical Name: 1,3-diphenylpropan-1-ol
• CAS No.: 14097-24-6
• Molecular Formula: C15H16 O
• Molecular Weight: 212.291
• NSC Number: 69141
• Nikkaji Number: J337.657E
• Mol file: 14097-24-6.mol

Synonyms:1-Propanol,1,3-diphenyl- (6CI,7CI,8CI); 1,3-Diphenyl-1-propanol; NSC 69141; a-Phenylbenzenepropanol

Chemical Property of 1,3-diphenylpropan-1-ol

Chemical Property:

• Vapor Pressure: 2.44E-05mmHg at 25°C
• Boiling Point: 344.9°Cat760mmHg
• Flash Point: 144.6°C
• Density: 1.073g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 212.120115130
• Heavy Atom Count: 16
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CCC(C2=CC=CC=C2)O

Technology Process of 1,3-diphenylpropan-1-ol

There total 234 articles about 1,3-diphenylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-Phenylethanol (98-85-1,13323-81-4) + benzyl alcohol (100-51-6,185532-71-2) → 1,3-diphenylpropan-1-ol (14097-24-6)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; rhodium(III) acetylacetonate; potassium hydroxide; In toluene; at 110 ℃; Sealed tube;

DOI:10.1002/adsc.201300061

Reference yield: 92.0%

(E)-1,3-diphenyl-2-propen-1-ol (62668-02-4) + 2-phenyl-1,3,2-benzodioxaborole (5747-23-9) → 1,3-diphenylpropan-1-ol (14097-24-6) + phenol (108-95-2,27073-41-2)

Guidance literature:

With oxygen; hydrazine hydrate; In acetonitrile; at 32 ℃; for 8h; under 760.051 Torr; Schlenk technique;

DOI:10.1002/ejoc.201501222

Reference yield: 80.0%

acetophenone (98-86-2) + benzyl alcohol (100-51-6,185532-71-2) → 1-Phenylethanol (98-85-1,13323-81-4) + dihydrochalcone (1083-30-3) + 1,3-diphenylpropan-1-ol (14097-24-6)

Guidance literature:

With potassium hydroxide; dichlorotetrakis(dimethyl sulfoxide)ruthenium(II); In 1,4-dioxane; at 80 ℃; for 24h;

DOI:10.1016/j.tet.2006.07.013

upstream raw materials:

3-phenyl-propionaldehyde

dihydrochalcone

phenethylmagnesium bromide

benzaldehyde

Downstream raw materials:

1,3-diphenylpropene

dihydrochalcone

cis-1,3-diphenylpropene

(1E)-1,3-diphenylpropene

Refernces

• 1、 Iba?ez,Poyatos,Peris. "Mono and dimetallic pyrene-imidazolylidene complexes of iridium(III) for the deuteration of organic substrates and the C-C coupling of alcohols". . p. 14154 - 14159. Retrieved 2016.
• 2、 Caputo,Ferreri,Palumbo,Pedatella. "Chemistry of ethanediyl S,S-acetals 9-asymmetric synthesis of chiral cis allylic alcohols". . p. 1517 - 1522. Retrieved 1995.
• 3、 Illam, Praseetha Mathoor,Rit, Arnab. "Electronically tuneable orthometalated RuII–NHC complexes as efficient catalysts for C–C and C–N bond formations via borrowing hydrogen strategy". . p. 67 - 74. Retrieved 2022/01/19.
• 4、 Liu, Jiahao,Li, Weikang,Li, Yinwu,Liu, Yan,Ke, Zhuofeng. "Selective C-alkylation Between Alcohols Catalyzed by N-Heterocyclic Carbene Molybdenum". supporting information. p. 3124 - 3128. Retrieved 2021/09/20.