1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate

Base Information

• Chemical Name: 1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate
• CAS No.: 1257520-46-9
• Molecular Formula: C₂₄H₃₁NO₄
• Molecular Weight: 397.514
• Mol file: 1257520-46-9.mol

Synonyms:1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate

Chemical Property of 1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate

There total 1 articles about 1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-phenyl-piperidine-4-carboxylic acid methyl ester; hydrochloride (83898-15-1) + 2-adamantyl chloroformate (53120-53-9) → 1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate (1257520-46-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Cooling with ice;

Reference yield:

1-(2-adamantyl) 4-methyl 4-phenylpiperidine-1,4-dicarboxylate (1257520-46-9) → 2-adamantyl 4-(hydroxymethyl)-4-phenylpiperidine-1-carboxylate (1257520-67-4)

Guidance literature:

With methanol; lithium borohydride; In tetrahydrofuran; at 20 ℃; for 96h;

upstream raw materials:

4-phenyl-piperidine-4-carboxylic acid methyl ester; hydrochloride

2-adamantyl chloroformate

Downstream raw materials:

2-adamantyl 4-(hydroxymethyl)-4-phenylpiperidine-1-carboxylate