3,5-Dichloro-2-oxo-1,2-dihydro-1-pyridineacetic acid ethyl ester

Base Information

• Chemical Name: 3,5-Dichloro-2-oxo-1,2-dihydro-1-pyridineacetic acid ethyl ester
• CAS No.: 25177-50-8
• Molecular Formula: C9H9 Cl2 N O3
• Molecular Weight: 250.08
• Hs Code.: 2933399090
• Mol file: 25177-50-8.mol

Synonyms:(3,5-Dichlor-2-oxo-2H-[1]pyridyl)-essigsaeure-aethylester;(3,5-dichloro-2-oxo-2H-[1]pyridyl)-acetic acid ethyl ester;ethyl(3,5-dichloro-2-oxopyridin-1(2h)-yl)acetate;1(2H)-Pyridineacetic acid,3,5-dichloro-2-oxo-,ethyl ester;3,5-Dichloro-2-oxo-1(2H)-pyridineacetic acid ethyl ester;Ethyl 3,5-dichloro-2-pyridone-1-acetate;

Chemical Property of 3,5-Dichloro-2-oxo-1,2-dihydro-1-pyridineacetic acid ethyl ester

Chemical Property:

• Vapor Pressure: 9.07E-05mmHg at 25°C
• Boiling Point: 339.6°C at 760 mmHg
• Flash Point: 159.2°C
• PSA: 48.30000
• Density: 1.42g/cm³
• LogP: 1.71820

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Dichloro-2-oxo-1,2-dihydro-1-pyridineacetic acid ethyl ester

There total 2 articles about 3,5-Dichloro-2-oxo-1,2-dihydro-1-pyridineacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Pyridone (142-08-5,1199357-22-6) → (3,5-dichloro-2-oxo-2H-[1]pyridyl)-acetic acid ethyl ester (25177-50-8)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous sulfuric acid; chlorine

With sulfuric acid; chlorine;

DOI:10.1021/jo01105a007

Reference yield:

diazoacetic acid ethyl ester (623-73-4) + 3,5-Dichloro-2-pyridinol (5437-33-2) → (3,5-dichloro-2-oxo-2H-[1]pyridyl)-acetic acid ethyl ester (25177-50-8) + (3,5-dichloro-[2]pyridyloxy)-acetic acid ethyl ester (68057-84-1)

Guidance literature:

DOI:10.1021/jo01105a007

upstream raw materials:

diazoacetic acid ethyl ester

3,5-Dichloro-2-pyridinol

2-Pyridone