Technology Process of C26H28FN5O4
There total 10 articles about C26H28FN5O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
tert-butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
for 0.5h;
C14H8ClFN4;
In
tetrahydrofuran; mineral oil;
for 2.5h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium nitrate; sulfuric acid / 2 h / 0 - 20 °C
2.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h / 20 °C / 760.05 Torr
3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C
3.2: 2.5 h / Reflux
4.1: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C
5.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C
5.2: 2.5 h / Reflux
With
hydrogenchloride; sulfuric acid; hydrogen; sodium hydride; potassium nitrate;
palladium 10% on activated carbon;
In
tetrahydrofuran; 1,4-dioxane; methanol; mineral oil;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h / 20 °C / 760.05 Torr
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C
2.2: 2.5 h / Reflux
3.1: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C
4.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C
4.2: 2.5 h / Reflux
With
hydrogenchloride; hydrogen; sodium hydride;
palladium 10% on activated carbon;
In
tetrahydrofuran; 1,4-dioxane; methanol; mineral oil;
![tert-butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate](/Databaselist/images/loading.webp)
