tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane

Base Information

• Chemical Name: tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane
• CAS No.: 137718-78-6
• Molecular Formula: C₁₃H₂₆O₂Si
• Molecular Weight: 242.434
• Mol file: 137718-78-6.mol

Synonyms:tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane

Chemical Property of tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane

There total 2 articles about tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-hydroxy-1-methoxy-1-cyclohexene (69125-55-9) + tert-butyldimethylsilyl chloride (18162-48-6) → tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane (137718-78-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; for 36h; Ambient temperature;

DOI:10.1021/jo00028a066

Reference yield:

4-methoxy-phenol (150-76-5) → tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane (137718-78-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / Li; NH₃ / diethyl ether; ethanol / 6 h / -33 °C

2: 99 percent / imidazole / tetrahydrofuran / 10 h / 22 °C

With 1H-imidazole; ammonia; lithium; In tetrahydrofuran; diethyl ether; ethanol; 1: Birch reduction;

DOI:10.1002/chem.200601240

Reference yield: 89.0%

tert-butyl-(4-methoxycyclohex-3-enyloxy)dimethylsilane (137718-78-6) → 2-bromo-4-(tert-butyldimethylsilyloxy)cyclohexanone (943589-86-4)

Guidance literature:

With N-Bromosuccinimide; sodium acetate; In tetrahydrofuran; water; at 22 ℃; for 4h;

DOI:10.1002/chem.200601240

upstream raw materials:

4-hydroxy-1-methoxy-1-cyclohexene

tert-butyldimethylsilyl chloride

4-methoxy-phenol

Downstream raw materials:

trans-2-bromo-4-(tert-butyldimethylsiloxy)cyclohexanone

cis-2-bromo-4-(tert-butyldimethylsiloxy)cyclohexanone

2-bromo-4-(tert-butyldimethylsilyloxy)cyclohexanone

(3-bromo-4-trifluoromethanesulfonyloxycyclohex-3-enyloxy)-tert-butyldimethylsilane