2,5-Dimethylbenzenesulfonohydrazide

Base Information

• Chemical Name: 2,5-Dimethylbenzenesulfonohydrazide
• CAS No.: 38045-54-4
• Molecular Formula: C8H12N2O2S
• Molecular Weight: 200.261
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID30366429
• Nikkaji Number: J3.114.692E
• Wikidata: Q82151640
• Mol file: 38045-54-4.mol

Synonyms:2,5-dimethylbenzenesulfonohydrazide;38045-54-4;2,5-dimethylbenzene-1-sulfonohydrazide;Oprea1_162316;SCHEMBL1868303;DTXSID30366429;BBL013855;MFCD02710371;STK409678;AKOS000116223;VS-04023;2,5-Dimethylbenzenesulfonic acid hydrazide;CS-0307619;EN300-03662;A913058;SR-01000029744;SR-01000029744-1;Z56796172

Chemical Property of 2,5-Dimethylbenzenesulfonohydrazide

Chemical Property:

• Vapor Pressure: 1.41E-05mmHg at 25°C
• Boiling Point: 367°Cat760mmHg
• Flash Point: 175.7°C
• PSA: 80.57000
• Density: 1.253g/cm³
• LogP: 2.62740
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 200.06194880
• Heavy Atom Count: 13
• Complexity: 258

Purity/Quality:

98%min ^*data from raw suppliers

2,5-dimethylbenzenesulfonohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C)S(=O)(=O)NN

Technology Process of 2,5-Dimethylbenzenesulfonohydrazide

There total 2 articles about 2,5-Dimethylbenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethylbenzenesulfonyl chloride (19040-62-1) → 2,5-dimethyl-benzenesulfonic acid hydrazide (38045-54-4)

Guidance literature:

With sodium hydroxide; hydrazinium sulfate; In water; at 20 - 90 ℃; pH=7.3;

DOI:10.1134/S0965544112040068

Reference yield:

→ 2,5-dimethyl-benzenesulfonic acid hydrazide (38045-54-4)

Guidance literature:

entspr. Sulfonsaeurechlorid, 1) Hydrazinsulfat, W., 20grad, 2) wss. NH3-Lsg., zuerst 3 h 25-35grad, dann 2 h 60-70grad, Ruehren;

Reference yield: 92.0%

2,5-dimethyl-benzenesulfonic acid hydrazide (38045-54-4) + naphthalen-2-ylamine (91-59-8) → 1-((2,5-dimethylphenyl)thio)naphthalen-2-amine

Guidance literature:

With tetra-(n-butyl)ammonium iodide; propylene glycol dimethyl ether dimer; at 100 ℃; for 12h; Schlenk technique;

DOI:10.1016/j.tet.2020.131646

upstream raw materials:

2,5-dimethylbenzenesulfonyl chloride

Downstream raw materials:

C₈H₁₂N₂O₂S*ClH

S-(2,5-dimethylphenyl) 2,5-dimethylbenzenesulfonothioate

Refernces

• 1、 Mamedov,Mamedova,Guseinov,Ladokhina,Fatalizade,Farzaliev. "Synthesis of N-substituted derivatives of arylsulfonyl hydrazides and their investigation as additives for lubricating oils". . p. 284 - 287. Retrieved 2012/10/29.