triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane

Base Information

• Chemical Name: triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane
• CAS No.: 107769-77-7
• Molecular Formula: C₃₁H₂₉N₂O₂P
• Molecular Weight: 492.557
• Mol file: 107769-77-7.mol

Synonyms:triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane

Chemical Property of triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane

There total 5 articles about triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propyl>phosphonium iodide (107769-76-6) → triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane (107769-77-7)

Guidance literature:

With sodium methylate; In methanol; at 0 ℃; for 0.5h;

DOI:10.1021/jo00385a029

Reference yield:

methyl 2-oxo-2-phenylacetate (15206-55-0) → triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane (107769-77-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 53 percent / aq. hydrazine, aq. HCl / methanol / 96 h / Ambient temperature

2: 75 percent / CH₂Cl₂ / 4 h / Heating

3: 85 percent / KOH / methanol / 0.5 h / -5 °C

4: 83 percent / acetonitrile / 0.5 h / Heating

5: 86 percent / NaOMe / methanol / 0.5 h / 0 °C

With hydrogenchloride; potassium hydroxide; sodium methylate; hydrazine hydrate; In methanol; dichloromethane; acetonitrile;

DOI:10.1021/jo00385a029

Reference yield:

methyl α-hydrazonophenylacetate (23102-11-6) → triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane (107769-77-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / CH₂Cl₂ / 4 h / Heating

2: 85 percent / KOH / methanol / 0.5 h / -5 °C

3: 83 percent / acetonitrile / 0.5 h / Heating

4: 86 percent / NaOMe / methanol / 0.5 h / 0 °C

With potassium hydroxide; sodium methylate; In methanol; dichloromethane; acetonitrile;

DOI:10.1021/jo00385a029

upstream raw materials:

triphenyl<1-methyl-2-((phenyl(methoxycarbonyl)methylene)hydrazono)propyl>phosphonium iodide

methyl 2-oxo-2-phenylacetate

methyl α-hydrazonophenylacetate

triphenyl<2-((phenyl(methoxycarbonyl)methylene)hydrazono)propylidene>phosphorane

Downstream raw materials:

2,3-dimethyl-9-phenyl-9H-pyrazolo<5,1-b><1,3>benzothiazine

{[2-[4-(2-{[1-Methoxycarbonyl-1-phenyl-meth-(Z)-ylidene]-hydrazono}-1-methyl-propylidene)-[1,3]dithietan-2-ylidene]-1-methyl-prop-(Z)-ylidene]-hydrazono}-phenyl-acetic acid methyl ester

trans-5,10-bis(methoxycarbonyl)-5,10-diphenylpyrazolo<1,5-a:1',5'-e><1,5>diaza<3,6>dithiocine

2,3-dimethyl-9-phenylpyrazolo<5,1-b>quinazoline