N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide

Base Information

• Chemical Name: N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide
• CAS No.: 19919-61-0
• Molecular Formula: C₁₆H₁₅N₃O₂S₂
• Molecular Weight: 345.446
• Mol file: 19919-61-0.mol

Synonyms:N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide

Chemical Property of N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide

There total 2 articles about N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

p-toluenesulfonyl chloride (98-59-9) + 2-amino-5-(4-methylphenyl)-1,3,4-thiadiazole (26907-54-0) → N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide (19919-61-0)

Guidance literature:

In pyridine; at 60 ℃; for 1h; Reflux;

DOI:10.1134/S1070328415050024

Reference yield:

→ N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide (19919-61-0)

Guidance literature:

Amid 1c, Hydrazid 2a;

Reference yield: 58.0%

pyridine (110-86-1) + copper(ll) sulfate pentahydrate + water (7732-18-5) + N-(5-(4-methylphenyl)-[13,4]-thiadiazole-2-yl)-toluenesulfonamide (19919-61-0) → C42H40CuN8O5S4

Guidance literature:

at 20 ℃; for 2h;

DOI:10.1134/S1070328415050024

upstream raw materials:

p-toluenesulfonyl chloride

2-amino-5-(4-methylphenyl)-1,3,4-thiadiazole