(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Base Information

Chemical Name:(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid
CAS No.:1383814-70-7
Molecular Formula:C₁₄H₁₆N₂O₄
Molecular Weight:276.292
Hs Code.:

Synonyms:(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Suppliers and Price of (2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 4 raw suppliers

Chemical Property of (2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of (2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

There total 3 articles about (2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.5%

: 1383814-71-8
(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1] octane-2-carboxylic acid cyclohexylamine salt

: 1383814-70-7,2064219-13-0
(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Guidance literature:: With sodium dihydrogenphosphate; In water;

Reference yield:

: 1383814-69-4
(2R,5S)-tert-butyl 6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate

: 1383814-70-7,2064219-13-0
(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

1.2: 1 h / 0 - 20 °C

2.1: sodium dihydrogenphosphate / water

With sodium dihydrogenphosphate; trifluoroacetic acid; In dichloromethane; water;

Reference yield:

: C₁₇H₂₆N₂O₃

: 1383814-70-7,2064219-13-0
(2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / acetonitrile / 0.25 h / 0 °C / Inert atmosphere

1.2: 3 h / 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

2.2: 1 h / 0 °C

3.1: sodium dihydrogenphosphate / water

With sodium dihydrogenphosphate; triethylamine; trifluoroacetic acid; In dichloromethane; water; acetonitrile;