(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid
CAS No.:1029649-75-9
Molecular Formula:C₁₆H₂₀ClNO₇
Molecular Weight:373.79
Hs Code.:

Synonyms:(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

Chemical Property:

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Technology Process of (R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

There total 1 articles about (R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1029649-73-7
(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid methyl ester

: 1029649-75-9
(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

Guidance literature:: With water; lithium hydroxide; In 1,4-dioxane; at 20 ℃; for 12h;
DOI:10.1021/jm901209q

Reference yield:

: 1029649-75-9
(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

: 108-91-8,157973-60-9
cyclohexylamine

: 1029650-74-5
C₂₂H₃₁ClN₂O₆

Guidance literature:: (R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid; With triethylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

cyclohexylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/jm901209q

Reference yield:

: 123-75-1
pyrrolidine

: 1029649-75-9
(R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid

: 1029650-80-3
C₂₀H₂₇ClN₂O₆

Guidance literature:: (R)-1-(5-chloro-2,4-bis-methoxymethoxy-benzoyl)-pyrrolidine-2-carboxylic acid; With triethylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

pyrrolidine; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/jm901209q