Cas 1029650-80-3,C20H27ClN2O6

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Check Digit Verification of cas no

The CAS Registry Mumber 1029650-80-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,9,6,5 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1029650-80:
(9*1)+(8*0)+(7*2)+(6*9)+(5*6)+(4*5)+(3*0)+(2*8)+(1*0)=143
143 % 10 = 3
So 1029650-80-3 is a valid CAS Registry Number.

1029650-80-3Upstream product

1029650-80-3Downstream Products

1023885-50-8 (5-chloro-2,4-dihydroxy-phenyl)-[(R)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-methanone

1029650-80-3Relevant academic research and scientific papers

Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (Hsp90) molecular chaperone

Kung, Pei-Pei,Huang, Buwen,Zhang, Gang,Zhou, Joe Zhongxiang,Wang, Jeff,Digits, Jennifer A.,Skaptason, Judith,Yamazaki, Shinji,Neul, David,Zientek, Michael,Elleraas, Jeff,Mehta, Pramod,Yin, Min-Jean,Hickey, Michael J.,Gajiwala, Ketan S.,Rodgers, Caroline,Davies II, Jay F.,Gehring, Michael R.

supporting information; experimental part, p. 499 - 503 (2010/06/11)

The discovery and optimization of potency and metabolic stability of a novel class of dihyroxyphenyl-isoindoline amides as Hsp90 inhibitors are presented. Optimization of a screening hit using structure-based design and modification of log D and chemical

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