[4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid

Base Information

Chemical Name:[4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid
CAS No.:1003314-29-1
Molecular Formula:C₂₄H₂₇N₂O₅PS
Molecular Weight:486.529
Hs Code.:

Synonyms:[4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid

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Chemical Property of [4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid

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Technology Process of [4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid

There total 1 articles about [4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1003314-25-7
[4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid ethyl ester

: 1003314-29-1
[4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid

Guidance literature:: [4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid ethyl ester; With sodium hydroxide; In 1,4-dioxane; water; at 60 ℃; for 18h;

With hydrogenchloride; In 1,4-dioxane; water;

Reference yield:

: 1003314-29-1
[4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid

: 2919-23-5
cyclobutanol

: [4-(2-tert-butoxycarbonylamino-5-thiophen-2-yl-phenylcarbamoyl)benzyl]-methyl-phosphinic acid cyclobutyl ester

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 18h;