2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Base Information

Chemical Name:2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside
CAS No.:798557-35-4
Molecular Formula:C₄₁H₄₆O₉
Molecular Weight:682.811
Hs Code.:

Synonyms:2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Suppliers and Price of 2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

There total 7 articles about 2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 798557-34-3
2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-6-iodo-2-O-pivaloyl-α-D-mannopyranoside

: 798557-35-4
2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; for 2h; Heating;
DOI:10.1021/ol048648u

Reference yield:

: 3282-30-2
pivaloyl chloride

: 798557-35-4
2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: 89 percent / DMAP; Et₃N / CH₂Cl₂ / 3.5 h / 0 °C

2.1: BH₃; Bu₂BOTf / tetrahydrofuran / 3 h / 0 °C

2.2: 93 percent / Et₃N / tetrahydrofuran / 1 h

3.1: 89 percent / PPh₃; imidazole; I₂ / toluene / 2 h / Heating

4.1: 91 percent / n-Bu₃SnH; AIBN / toluene / 2 h / Heating

With 1H-imidazole; dmap; 2,2'-azobis(isobutyronitrile); di-n-butylboryl trifluoromethanesulfonate; borane; iodine; tri-n-butyl-tin hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/ol048648u

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 798557-35-4
2'-(benzyloxycarbonyl)benzyl 4-O-benzyl-6-deoxy-3-O-p-methoxybenzyl-2-O-pivaloyl-α-D-rhamnopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1.1: Bu₂SnO / methanol / 1 h / 60 °C

1.2: 83 percent / Bu₄NI / dimethylformamide / 1.5 h / 90 °C

2.1: 89 percent / DMAP; Et₃N / CH₂Cl₂ / 3.5 h / 0 °C

3.1: BH₃; Bu₂BOTf / tetrahydrofuran / 3 h / 0 °C

3.2: 93 percent / Et₃N / tetrahydrofuran / 1 h

4.1: 89 percent / PPh₃; imidazole; I₂ / toluene / 2 h / Heating

5.1: 91 percent / n-Bu₃SnH; AIBN / toluene / 2 h / Heating

With 1H-imidazole; dmap; 2,2'-azobis(isobutyronitrile); di-n-butylboryl trifluoromethanesulfonate; borane; iodine; tri-n-butyl-tin hydride; di(n-butyl)tin oxide; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/ol048648u