N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine

Base Information

• Chemical Name: N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine
• CAS No.: 158094-51-0
• Molecular Formula: C₃₆H₆₂N₄
• Molecular Weight: 550.915
• Mol file: 158094-51-0.mol

Synonyms:N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine

Chemical Property of N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine

There total 1 articles about N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) + N,N'-bis(6-aminohexyl)-N,N'-dimethyl-1,8-octanediamine (115962-75-9) → N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine (158094-51-0)

Guidance literature:

With sodium tetrahydroborate; Yield given. Multistep reaction; 1.) benzene, reflux, 6 h, 2.) EtOH, RT, 3 h;

DOI:10.1021/jm00075a032

Reference yield: 32.0%

11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one (28797-48-0) + N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine (158094-51-0) → C64H80N10O4 (152429-66-8)

Guidance literature:

With triethylamine; potassium iodide; In N,N-dimethyl-formamide; for 72h; Ambient temperature;

DOI:10.1021/jm00075a032

Reference yield:

N,N'-Bis-(6-benzylamino-hexyl)-N,N'-dimethyl-octane-1,8-diamine (158094-51-0) → C57H74N10O4 (152429-67-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 32 percent / Et₃N, KI / dimethylformamide / 72 h / Ambient temperature

2: 24 percent / H₂, 3 N HCl / 10percent Pd/C / ethanol / 12 h / 50 °C / 3800 Torr

With hydrogenchloride; hydrogen; triethylamine; potassium iodide; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00075a032

upstream raw materials:

benzaldehyde

N,N'-bis(6-aminohexyl)-N,N'-dimethyl-1,8-octanediamine

Downstream raw materials:

C₆₄H₈₀N₁₀O₄

C₅₇H₇₄N₁₀O₄

C₇₁H₈₃N₁₃O₆

Tripitramine