4-Methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide

Base Information

• Chemical Name: 4-Methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide
• CAS No.: 37481-38-2
• Molecular Formula: C₁₈H₂₀N₂O₂
• Molecular Weight: 296.369
• Hs Code.: 2933499090
• Mol file: 37481-38-2.mol

Synonyms:5-(4-Methoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline;Isoquinoline,1,2,3,4-tetrahydro-5-(4-methoxybenzamido)-2-methyl;4-methoxy-N-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide;1,2,3,4-TETRAHYDRO-5-(4-METHOXYBENZAMIDO)-2-METHYLISOQUINOLINE;Benzamide,4-methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl);4-Methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide;

Chemical Property of 4-Methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide

Chemical Property:

• Vapor Pressure: 4.35E-06mmHg at 25°C
• Boiling Point: 383.6°C at 760 mmHg
• Flash Point: 185.8°C
• PSA: 41.57000
• Density: 1.184g/cm³
• LogP: 2.94630

Purity/Quality:

99% ^*data from raw suppliers

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Technology Process of 4-Methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide

There total 2 articles about 4-Methoxy-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline (14097-41-7) + 4-methoxy-benzoyl chloride (100-07-2) → 4-methoxy-N-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide (37481-38-2)

Guidance literature:

Reference yield:

→ 4-methoxy-N-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide (37481-38-2)

Guidance literature:

entspr. 5-Nitro-isochinolin, entspr. Alkylhalogenid;

DOI:10.1021/jm00262a005

upstream raw materials:

5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline

4-methoxy-benzoyl chloride

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