benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

Base Information

Chemical Name:benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate
CAS No.:949495-19-6
Molecular Formula:C₁₆H₂₀N₂O₄
Molecular Weight:304.346
Hs Code.:

Synonyms:benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

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Chemical Property of benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

Chemical Property:

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Technology Process of benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

There total 8 articles about benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1373613-95-6
benzyl 3-(cyclopropylcarbamoyl)-4-oxopyrrolidine-1-carboxylate

: 949495-13-0
benzyl (3S,4R)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

: 949495-19-6
benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

Guidance literature:: With dichloro(benzene)ruthenium(II) dimer; hydrogen; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); In toluene; at 80 ℃; under 3750.38 - 4500.45 Torr; Time; Solvent; Pressure; Temperature;

Reference yield:

: 1373613-95-6
benzyl 3-(cyclopropylcarbamoyl)-4-oxopyrrolidine-1-carboxylate

: 949495-13-0
benzyl (3S,4R)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

: 949495-19-6
benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

: C₁₆H₂₀N₂O₄

Guidance literature:: With dichloro(benzene)ruthenium(II) dimer; hydrogen; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); In 2,2,2-trifluoroethanol; at 60 ℃; under 3750.38 - 4500.45 Torr; Time; Solvent;

Reference yield:

: 949495-18-5
(3R,4S)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-3-carboxylic acid

: 765-30-0
Cyclopropylamine

: 949495-19-6
benzyl (3R,4S)-3-(cyclopropylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃; for 5h;