p-hydroxyphenylacetaldehyde oxime

Base Information

• Chemical Name: p-hydroxyphenylacetaldehyde oxime
• CAS No.: 70365-10-5
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.165
• Mol file: 70365-10-5.mol

Synonyms:p-hydroxyphenylacetaldehyde oxime

Chemical Property of p-hydroxyphenylacetaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-hydroxyphenylacetaldehyde oxime

There total 3 articles about p-hydroxyphenylacetaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxyphenylacetaldehyde (7339-87-9) → 4-hydroxyphenylacetaldoxime (70365-12-7) + p-hydroxyphenylacetaldehyde oxime (70365-10-5)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; at 20 ℃; for 6h; Title compound not separated from byproducts;

DOI:10.1016/S0968-0896(03)00241-4

Reference yield:

4-hydroxyphenylacetate (156-38-7) → p-hydroxyphenylacetaldehyde oxime (70365-10-5)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂SO₄ / 2 h / Heating

2: 75 percent / DIBAL-H / toluene / 5 h / -78 °C

3: NH₂OH*HCl; aq. NaOAc / aq. ethanol / 6 h / 20 °C

With sulfuric acid; hydroxylamine hydrochloride; sodium acetate; diisobutylaluminium hydride; In ethanol; toluene;

DOI:10.1016/S0968-0896(03)00241-4

Reference yield:

→ p-hydroxyphenylacetaldehyde oxime (70365-10-5)

Guidance literature:

4-Hydroxy-ω-nitro-styrol i. Methanol + Pt, Zn-Pulver, Essigsaeure, 30-35grad, Nebenprod.:Syn-Verb.;

DOI:10.1007/BF00900200

upstream raw materials:

4-hydroxyphenylacetaldehyde

4-hydroxyphenylacetate