(Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

Base Information

Chemical Name:(Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate
CAS No.:1586740-69-3
Molecular Formula:C₁₀H₉BrINO₂
Molecular Weight:381.995
Hs Code.:

Synonyms:(Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

Suppliers and Price of (Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

There total 3 articles about (Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 1586740-56-8
(Z)-methyl 3-(2-aminophenyl)-2-bromoacrylate

: 1586740-69-3
(Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

: 1586740-70-6
(Z)-methyl 3-(2-amino-3,5-diiodophenyl)-2-bromoacrylate

Guidance literature:: With dihydrogen peroxide; acetic acid; potassium iodide; for 16h;
DOI:10.1016/j.tetlet.2013.10.048

Reference yield:

: 552-89-6
2-nitro-benzaldehyde

: 1586740-69-3
(Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: dimethylbromosulphonium bromide / dichloromethane / 1 h / 20 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: acetic acid; iron / ethanol / 0.08 h / 20 °C / Reflux

3.1: acetic acid; potassium iodide; dihydrogen peroxide / 16 h

With dihydrogen peroxide; iron; dimethylbromosulphonium bromide; acetic acid; potassium iodide; In ethanol; dichloromethane;
DOI:10.1016/j.tetlet.2013.10.048

Reference yield:

: 1402454-70-9
methyl (Z)-2-bromo-3-(2-nitrophenyl)propenoate

: 1586740-69-3
(Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; iron / ethanol / 0.08 h / 20 °C / Reflux

2: acetic acid; potassium iodide; dihydrogen peroxide / 16 h

With dihydrogen peroxide; iron; acetic acid; potassium iodide; In ethanol;
DOI:10.1016/j.tetlet.2013.10.048