1586740-56-8

Basic information

• Product Name: (Z)-methyl 3-(2-aminophenyl)-2-bromoacrylate
• Synonyms: (Z)-methyl 3-(2-aminophenyl)-2-bromoacrylate
• CAS NO: 1586740-56-8
• Molecular Weight: 256.099
• Mol File: 1586740-56-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-methyl 3-(2-aminophenyl)-2-bromoacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-methyl 3-(2-aminophenyl)-2-bromoacrylate(1586740-56-8)
• EPA Substance Registry System: (Z)-methyl 3-(2-aminophenyl)-2-bromoacrylate(1586740-56-8)

Safety Data

• Hazardous Substances Data: 1586740-56-8(Hazardous Substances Data)

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 1402454-70-9 methyl (Z)-2-bromo-3-(2-nitrophenyl)propenoate 

Downstream Products

• 1586740-68-2 (Z)-methyl 3-(2-amino-5-bromophenyl)-2-bromoacrylate 
• 1586740-69-3 (Z)-methyl 3-(2-amino-5-iodophenyl)-2-bromoacrylate 
• 1586740-70-6 (Z)-methyl 3-(2-amino-3,5-diiodophenyl)-2-bromoacrylate 
• 1586740-74-0 (Z)-3-(2-aminophenyl)-2-bromoacrylamide 
• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 210345-56-5 5-bromo-1H-indole-2-carboxylic acid methyl ester 
• 1670-84-4 1H-indole-2-carboxamide 
• 1586740-71-7 (Z)-methyl 3-(2-acetamidophenyl)-2-bromoacrylate 
• 1586740-72-8 (Z)-propyl 2-bromo-3-(2-aminophenyl)acrylate 
• 1586740-73-9 (Z)-isopropyl 2-bromo-3-(2-aminophenyl)acrylate 

Relevant articles and documents

CuI-catalyzed intramolecular cyclization of 3-(2-aminophenyl)-2- bromoacrylate: Synthesis of 2-carboxyindoles

A new approach was described for the synthesis of substituted 2-carboxyindole using 3-(2-aminophenyl)-2-bromo-acrylates through a CuI-catalyzed intramolecular coupling. The reactions were mild, rapid and with good to excellent yields.