9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

Base Information

Chemical Name:9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol
CAS No.:1378239-11-2
Molecular Formula:C₂₀H₂₂O₅
Molecular Weight:342.392
Hs Code.:

Synonyms:9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

Suppliers and Price of 9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

There total 6 articles about 9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 1378238-99-3
3,4-dimethoxy-9-(3',4',5'-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

: 1378239-11-2
9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

: 1378239-13-4
3-methoxy-4-hydroxy-9-(3',4'-dihydroxy-5'-methoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

: 1378239-12-3
3,4-dimethoxy-9-(3',5'-dimethoxy-4'-hydroxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

Guidance literature:: 3,4-dimethoxy-9-(3',4',5'-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene; With trimethylammonium heptachlorodialuminate; at 80 ℃; for 1h; Microwave irradiation; Inert atmosphere; Sealed tube;

With water;

Reference yield:

: 86-51-1
2,3-dimethyoxybenzaldehyde

: 1378239-11-2
9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

: 1378239-13-4
3-methoxy-4-hydroxy-9-(3',4'-dihydroxy-5'-methoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

: 1378239-12-3
3,4-dimethoxy-9-(3',5'-dimethoxy-4'-hydroxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

Guidance literature:: Multi-step reaction with 6 steps

1.1: potassium tert-butylate / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C

2.1: hydrogen / palladium 10% on activated carbon / methanol / 24 h

3.1: methanesulfonic acid; phosphorus pentoxide / 12 h / Inert atmosphere

4.1: n-butyllithium / tetrahydrofuran; hexanes / 1 h / -78 °C

4.2: -78 - 20 °C

4.3: 20 °C

5.1: acetic acid / 4 h / Reflux

6.1: trimethylammonium heptachlorodialuminate / 1 h / 80 °C / Microwave irradiation; Inert atmosphere; Sealed tube

With n-butyllithium; methanesulfonic acid; phosphorus pentoxide; trimethylammonium heptachlorodialuminate; potassium tert-butylate; hydrogen; acetic acid; palladium 10% on activated carbon; In tetrahydrofuran; methanol; hexanes; 1.1: Wittig Reaction;

Reference yield:

: 1378238-71-1
(Z)/(E)-5-(2',3'-dimethoxyphenyl)pent-4-enoic acid

: 1378239-11-2
9-(4'-Hydroxy-3',5'-dimethoxyphenyl)-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-4-ol

: 1378239-13-4
3-methoxy-4-hydroxy-9-(3',4'-dihydroxy-5'-methoxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

: 1378239-12-3
3,4-dimethoxy-9-(3',5'-dimethoxy-4'-hydroxyphenyl)-6,7-dihydro-5H-benzo[7]annulene

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogen / palladium 10% on activated carbon / methanol / 24 h

2.1: methanesulfonic acid; phosphorus pentoxide / 12 h / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran; hexanes / 1 h / -78 °C

3.2: -78 - 20 °C

3.3: 20 °C

4.1: acetic acid / 4 h / Reflux

5.1: trimethylammonium heptachlorodialuminate / 1 h / 80 °C / Microwave irradiation; Inert atmosphere; Sealed tube

With n-butyllithium; methanesulfonic acid; phosphorus pentoxide; trimethylammonium heptachlorodialuminate; hydrogen; acetic acid; palladium 10% on activated carbon; In tetrahydrofuran; methanol; hexanes;