methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate

Base Information

• Chemical Name: methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate
• CAS No.: 1337542-13-8
• Molecular Formula: C₂₅H₂₈N₂O₆
• Molecular Weight: 452.507
• Mol file: 1337542-13-8.mol

Synonyms:methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate

Chemical Property of methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate

There total 4 articles about methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.5%

methyl 12-bromo-13-nitro-7-oxo-dehydrodeisopropylabietate (41437-48-3) + 4-methoxy-aniline (104-94-9) → methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate (1337542-13-8)

Guidance literature:

methyl 12-bromo-13-nitro-7-oxo-dehydrodeisopropylabietate; With potassium carbonate; copper(l) chloride; In N,N-dimethyl-formamide;

4-methoxy-aniline; In N,N-dimethyl-formamide; at 100 ℃;

DOI:10.1007/s00044-011-9766-2

Reference yield:

dehydroabietic acid (1740-19-8) → methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate (1337542-13-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: acetone

2.1: N-Bromosuccinimide / Darkness

3.1: chromium(VI) oxide

4.1: nitric acid; sulfuric acid / Cooling

5.1: potassium carbonate; copper(l) chloride / N,N-dimethyl-formamide

5.2: 100 °C

With chromium(VI) oxide; N-Bromosuccinimide; sulfuric acid; nitric acid; potassium carbonate; copper(l) chloride; In N,N-dimethyl-formamide; acetone; 5.2: |Ullmann Condensation;

DOI:10.1007/s00044-011-9766-2

Reference yield:

Methyl dehydroabietate (1235-74-1,1757-97-7,2756-34-5,7151-00-0,10178-27-5,10178-29-7,21699-55-8,24035-60-7) → methyl 12-(p-methoxyphenyl)amino-13-nitro-7-oxodehydrodeisopropylabietate (1337542-13-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: N-Bromosuccinimide / Darkness

2.1: chromium(VI) oxide

3.1: nitric acid; sulfuric acid / Cooling

4.1: potassium carbonate; copper(l) chloride / N,N-dimethyl-formamide

4.2: 100 °C

With chromium(VI) oxide; N-Bromosuccinimide; sulfuric acid; nitric acid; potassium carbonate; copper(l) chloride; In N,N-dimethyl-formamide; 4.2: |Ullmann Condensation;

DOI:10.1007/s00044-011-9766-2

upstream raw materials:

dehydroabietic acid

methyl 12-bromo-13-nitro-7-oxo-dehydrodeisopropylabietate

4-methoxy-aniline

Methyl dehydroabietate