(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol

Base Information

Chemical Name:(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol
CAS No.:78450-97-2
Molecular Formula:C₅H₃ClF₃NOS
Molecular Weight:217.599
Hs Code.:
DSSTox Substance ID:DTXSID20513804
Wikidata:Q82373790

Synonyms:(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol;78450-97-2;[2-Chloro-4-(trifluoromethyl)-1,3-thiazol-5-yl]methanol;SCHEMBL11153799;DTXSID20513804;CS-0379580;2-chloro-4-(trifluoromethyl)-5-thiazolemethanol;A865026

Suppliers and Price of (2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol 95+%
1g
$ 705.00

Chemenu
(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol 95%
1g
$ 659.00

Alichem
(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol
1g
$ 596.40

Total 4 raw suppliers

Chemical Property of (2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:216.9575971
Heavy Atom Count:12
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C(C1=C(N=C(S1)Cl)C(F)(F)F)O

Technology Process of (2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol

There total 2 articles about (2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 72850-52-3
ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate

: 78450-97-2
2-Chloro-4-(trifluoromethyl)-5-thiazolemethanol

Guidance literature:: With sodium tetrahydroborate; In ethanol; 1.) 50 deg C, 5 min, exothermic reaction, 2.) 28 deg C, 30 min;;

Reference yield:

: 72850-53-4
ethyl 2,3-dihydro-2-oxo-4-trifluoromethyl-5-thiazole-carboxylate

: 78450-97-2
2-Chloro-4-(trifluoromethyl)-5-thiazolemethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / POCl₃ / Heating

2: 84 percent / NaBH₄ / ethanol / 1.) 50 deg C, 5 min, exothermic reaction, 2.) 28 deg C, 30 min;

With sodium tetrahydroborate; trichlorophosphate; In ethanol;