Technology Process of (3R,4S)-3-(benzyloxy)tetrahydro-2H-pyran-4-amine
There total 8 articles about (3R,4S)-3-(benzyloxy)tetrahydro-2H-pyran-4-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3S)-3-(benzyloxy)-tetrahydro-4H-pyran-4-one;
With
hydrogenchloride; disodium hydrogenphosphate; L-alanin; FDH; LDH; TA P1G5; nicotinamide adenine dinucleotide; pyridoxal 5'-phosphate; sodium formate;
In
water;
at 30 ℃;
for 15h;
pH=7.25;
Enzymatic reaction;
With
potassium carbonate;
In
water;
- Guidance literature:
-
L-alanin; (3S)-3-(benzyloxy)-tetrahydro-4H-pyran-4-one;
With
hydrogenchloride; disodium hydrogenphosphate; sodium formate; nicotiamide adenine dinucleotide;
In
water;
at 30 ℃;
for 15h;
pH=7.25 - 7.5;
Enzymatic reaction;
With
potassium carbonate;
In
water;
Enzymatic reaction;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium hydroxide; iodine / 2.17 h / 5 °C
2.1: sodium bromate; acetic acid / ruthenium(III) trichloride hydrate / acetonitrile; water / 2 h / 30 °C
3.1: D-glucose; sodium dihydrogenphosphate; KRED-130; GDH-103; β-nicotinamide adenine dinucleotide phosphate / water / 17 h / 30 °C / pH 7.02 / Enzymatic reaction
3.2: 0.5 h
4.1: sodium t-butanolate / tetrahydrofuran / 2 h / 22 - 35 °C / Inert atmosphere
4.2: 2 h / 50 °C / Inert atmosphere
5.1: hydrogenchloride / water; tetrahydrofuran / 1.5 h
5.2: pH 7.4
6.1: hydrogenchloride; sodium formate; disodium hydrogenphosphate; L-alanin; pyridoxal 5'-phosphate; FDH; LDH; TA P1G5; nicotinamide adenine dinucleotide / water / 15 h / 30 °C / pH 7.25 / Enzymatic reaction
With
hydrogenchloride; sodium bromate; disodium hydrogenphosphate; sodium dihydrogenphosphate; KRED-130; L-alanin; D-glucose; FDH; GDH-103; LDH; TA P1G5; nicotinamide adenine dinucleotide; β-nicotinamide adenine dinucleotide phosphate; pyridoxal 5'-phosphate; iodine; sodium formate; acetic acid; potassium hydroxide; sodium t-butanolate;
ruthenium(III) trichloride hydrate;
In
tetrahydrofuran; water; acetonitrile;
