Normethandrone

Base Information

• Chemical Name: Normethandrone
• CAS No.: 514-61-4
• Molecular Formula: C19H28O2
• Molecular Weight: 288.43
• Hs Code.: 29372900
• European Community (EC) Number: 208-183-0
• UNII: 743F1Z557A
• DSSTox Substance ID: DTXSID4023383
• Nikkaji Number: J6.289H
• Wikipedia: Normethandrone
• Wikidata: Q6824007
• NCI Thesaurus Code: C95970
• Metabolomics Workbench ID: 154331
• ChEMBL ID: CHEMBL2106801
• Mol file: 514-61-4.mol

Synonyms:17-alpha-methyl-19-nortestosterone;methylestrenolone;methylnortestosterone;methyloestrenolone;normethandrolone

Chemical Property of Normethandrone

Chemical Property:

• Appearance/Colour: white solid
• Vapor Pressure: 2.22E-09mmHg at 25°C
• Melting Point: 153-158 °C
• Refractive Index: 1.56
• Boiling Point: 434.6 °C at 760 mmHg
• PKA: 15.13±0.40(Predicted)
• Flash Point: 185.4 °C
• PSA: 37.30000
• Density: 1.12 g/cm³
• LogP: 3.87920
• Storage Temp.: Controlled Substance, -20°C Freezer
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 288.208930132
• Heavy Atom Count: 21
• Complexity: 508

Purity/Quality:

99%, ^*data from raw suppliers

NORMETHANDRONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2(C)O)CCC4=CC(=O)CCC34
• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CCC4=CC(=O)CC[C@H]34
• Uses: Androgen. Controlled substance (anabolic steroid).

Technology Process of Normethandrone

There total 12 articles about Normethandrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ normethandrolone (514-61-4)

Guidance literature:

With hydrogenchloride; ammonia; lithium;

DOI:10.1021/ja01645a010

Reference yield:

19-nortestosterone (434-22-0) → normethandrolone (514-61-4)

Guidance literature:

Multi-step reaction with 3 steps

1: CrO₃

3: aqueous HCl

With chromium(VI) oxide; hydrogenchloride;

DOI:10.1021/ja01645a010

Reference yield:

estra-4-ene-3,17-dione (734-32-7) → normethandrolone (514-61-4)

Guidance literature:

Multi-step reaction with 2 steps

2: aqueous HCl

With hydrogenchloride;

DOI:10.1021/ja01645a010

upstream raw materials:

3-ethoxy-19-nor-3,5-androstadiene-17-one

methylmagnesium bromide

3,3-ethanediyldioxy-17ξ-hydroxy-estr-5-ene-17ξ-carbonitrile

3,3-ethanediyldioxy-17α-methyl-estr-5-en-17β-ol

Downstream raw materials:

17α-methyl-3,17β-dihydroxyestr-1,3,5(10)-trien-6-one

17-methyl-estra-1,3,5(10)-triene-3,17α-diol

17α-methyl-11β,17β-dihydroxyestr-4-en-3-one

17,17-Dimethyl-gona-4,13-dien-3-on