(S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride

Base Information

Chemical Name:(S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride
CAS No.:248921-70-2
Molecular Formula:C₂₃H₃₀F₂N₂O*ClH
Molecular Weight:424.962
Hs Code.:
ChEMBL ID:CHEMBL452325

Synonyms:CHEMBL452325;WHSQHGGETBFMLM-FTBISJDPSA-N;(S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride;(S)-4-Methyl-2-methylamino-pentanoic acid [4,4-bis-(4-fluoro-phenyl)-butyl]-amide monohydrochloride

Suppliers and Price of (S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:424.2092976
Heavy Atom Count:29
Complexity:422

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC(C(=O)NCCCC(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)NC.Cl
Isomeric SMILES:CC(C)C[C@@H](C(=O)NCCCC(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)NC.Cl

Technology Process of (S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride

There total 3 articles about (S)-4-methyl-2-(methylamino)pentanoic acid [4,4-bis(4-fluorophenyl)butyl]amide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 248922-88-5
(S)-{1-[4,4-bis-(4-fluoro-phenyl)-butylcarbamoyl]-3-methyl-butyl}-methyl-carbamic acid tert-butyl ester

: 248921-70-2
(S)-4-Methyl-2-methylamino-pentanoic acid [4,4-bis-(4-fluoro-phenyl)-butyl]-amide monohydrochloride

Guidance literature:: With hydrogenchloride; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; chloroform;

Reference yield:

: 53363-89-6
N-t-butoxycarbonyl-N-methyl-L-leucine

: 248921-70-2
(S)-4-Methyl-2-methylamino-pentanoic acid [4,4-bis-(4-fluoro-phenyl)-butyl]-amide monohydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / diethyl ether; N,N-dimethyl-formamide

2: hydrogenchloride; trifluoroacetic acid / methanol; diethyl ether; dichloromethane; chloroform

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; chloroform; N,N-dimethyl-formamide;

Reference yield:

: 4,4-bis-(4-fluoro-phenyl)-butylamine monohydrochloride

: 248921-70-2
(S)-4-Methyl-2-methylamino-pentanoic acid [4,4-bis-(4-fluoro-phenyl)-butyl]-amide monohydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / diethyl ether; N,N-dimethyl-formamide

2: hydrogenchloride; trifluoroacetic acid / methanol; diethyl ether; dichloromethane; chloroform

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; chloroform; N,N-dimethyl-formamide;