2-benzoyl-5-bromobenzoic acid methyl ester

Base Information

• Chemical Name: 2-benzoyl-5-bromobenzoic acid methyl ester
• CAS No.: 1245735-29-8
• Molecular Formula: C₁₅H₁₁BrO₃
• Molecular Weight: 319.155
• Mol file: 1245735-29-8.mol

Synonyms:2-benzoyl-5-bromobenzoic acid methyl ester

Chemical Property of 2-benzoyl-5-bromobenzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-benzoyl-5-bromobenzoic acid methyl ester

There total 3 articles about 2-benzoyl-5-bromobenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

5-bromo-2-iodo-benzoic acid methyl ester (181765-86-6) + benzyl alcohol (100-51-6,185532-71-2) → 2-benzoyl-5-bromobenzoic acid methyl ester (1245735-29-8)

Guidance literature:

With tert.-butylhydroperoxide; palladium diacetate; silver(l) oxide; In water; at 120 ℃; for 22h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejoc.201900769

Reference yield:

5-bromo-2-iodo-benzoic acid methyl ester (181765-86-6) + benzoyl chloride (98-88-4) → 2-benzoyl-5-bromobenzoic acid methyl ester (1245735-29-8)

Guidance literature:

5-bromo-2-iodo-benzoic acid methyl ester; With isopropylmagnesium chloride; In tetrahydrofuran;

benzoyl chloride; In tetrahydrofuran; at -15 ℃; for 1h;

With ammonium chloride; In tetrahydrofuran; water;

Reference yield:

→ 2-benzoyl-5-bromobenzoic acid methyl ester (1245735-29-8)

Guidance literature:

upstream raw materials:

5-bromo-2-iodo-benzoic acid methyl ester

benzoyl chloride

benzyl alcohol

Downstream raw materials:

2-benzoyl-5-iodobenzoic acid methyl ester