(2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Base Information

Chemical Name:(2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide
CAS No.:500220-31-5
Molecular Formula:C₂₂H₃₉NO₅Si
Molecular Weight:425.641
Hs Code.:

Synonyms:(2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Suppliers and Price of (2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

There total 7 articles about (2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 866530-02-1
(2S,3R)-N-methoxy-N-methyl-3-hydroxy-5-(4-methoxybenzyloxy)-2-methylpentamide

: 500220-31-5
(2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Guidance literature:: With 1H-imidazole; dmap; In N,N-dimethyl-formamide; at 20 ℃; for 20h;
DOI:10.1021/ja061938g

Reference yield:

: 69739-34-0
t-butyldimethylsiyl triflate

: 866530-02-1
(2S,3R)-N-methoxy-N-methyl-3-hydroxy-5-(4-methoxybenzyloxy)-2-methylpentamide

: 500220-31-5
(2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at 25 ℃;
DOI:10.1021/ol027211o

Reference yield:

: 900171-30-4
(3S,4R)-4-[2-(4-methoxybenzyloxy)ethyl]-3-methyloxetan-2-one

: 500220-31-5
(2S,3R)-N-methoxy-N-methyl-3-(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2-methylpentamide

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylaluminum chloride / CH₂Cl₂; hexane / 2 h / -25 °C

2: imidazole; DMAP / dimethylformamide / 20 h / 20 °C

With 1H-imidazole; dmap; dimethylaluminum chloride; In hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja061938g