<1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Base Information

Chemical Name:<1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester
CAS No.:127980-34-1
Molecular Formula:C₁₇H₂₂O₄
Molecular Weight:290.359
Hs Code.:

Synonyms:<1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Suppliers and Price of <1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

There total 9 articles about <1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127980-30-7
<2-(3-bromophenyl)ethoxy>dimethyl(1,1,2-trimethylpropyl)silane

: 127980-34-1
<1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) tBuLi / 1.) ether, -78 deg C, 2.) ether, THF, from -78 deg C to 0 deg C

2: H₂, AcOH / 20 percent Pd(OH)2-C / 760 Torr

3: DMAP, pyridine / 25 °C

4: CrO₃, H₂SO₄ / acetone / 0 - 25 °C

5: aq. NaOH / tetrahydrofuran / 25 °C

6: HCl / 0 °C

With pyridine; chromium(VI) oxide; hydrogenchloride; dmap; sodium hydroxide; sulfuric acid; hydrogen; tert.-butyl lithium; acetic acid; palladium hydroxide - carbon; In tetrahydrofuran; acetone;
DOI:10.1021/jm00062a013

Reference yield:

: 127980-31-8
(3-{2-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-ethyl}-phenyl)-((1S,2S,3R,4R)-3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-yl)-methanol

: 127980-34-1
<1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: H₂, AcOH / 20 percent Pd(OH)2-C / 760 Torr

2: DMAP, pyridine / 25 °C

3: CrO₃, H₂SO₄ / acetone / 0 - 25 °C

4: aq. NaOH / tetrahydrofuran / 25 °C

5: HCl / 0 °C

With pyridine; chromium(VI) oxide; hydrogenchloride; dmap; sodium hydroxide; sulfuric acid; hydrogen; acetic acid; palladium hydroxide - carbon; In tetrahydrofuran; acetone;
DOI:10.1021/jm00062a013

Reference yield:

: 404575-34-4
7-oxabicyclo<2.2.1>heptane tetrahydrofuranol

: 127980-34-1
<1S-1α,2α,3α,4α>-3-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzeneacetic acid, methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) tBuLi / 1.) ether, -78 deg C, 2.) ether, THF, from -78 deg C to 0 deg C

2: H₂, AcOH / 20 percent Pd(OH)2-C / 760 Torr

3: DMAP, pyridine / 25 °C

4: CrO₃, H₂SO₄ / acetone / 0 - 25 °C

5: aq. NaOH / tetrahydrofuran / 25 °C

6: HCl / 0 °C

With pyridine; chromium(VI) oxide; hydrogenchloride; dmap; sodium hydroxide; sulfuric acid; hydrogen; tert.-butyl lithium; acetic acid; palladium hydroxide - carbon; In tetrahydrofuran; acetone;
DOI:10.1021/jm00062a013