Technology Process of 3-formyl-4-vinylbenzoic acid methyl ester
There total 3 articles about 3-formyl-4-vinylbenzoic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
caesium carbonate; triphenylphosphine; palladium dichloride;
In
tetrahydrofuran; water;
at 85 ℃;
for 22h;
sealed tube;
Inert atmosphere;
DOI:10.1039/c1cc10683j
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sulfuric acid; water / methanol / 1 h / Reflux; Inert atmosphere
1.2: 3 h / Reflux; Inert atmosphere
2.1: caesium carbonate; triphenylphosphine; palladium dichloride / tetrahydrofuran; water / 22 h / 85 °C / sealed tube; Inert atmosphere
With
sulfuric acid; water; caesium carbonate; triphenylphosphine; palladium dichloride;
In
tetrahydrofuran; methanol; water;
DOI:10.1039/c1cc10683j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: chromium(VI) oxide; sulfuric acid / 1.5 h / Cooling with ice; Inert atmosphere
2.1: sulfuric acid; water / methanol / 1 h / Reflux; Inert atmosphere
2.2: 3 h / Reflux; Inert atmosphere
3.1: caesium carbonate; triphenylphosphine; palladium dichloride / tetrahydrofuran; water / 22 h / 85 °C / sealed tube; Inert atmosphere
With
chromium(VI) oxide; sulfuric acid; water; caesium carbonate; triphenylphosphine; palladium dichloride;
In
tetrahydrofuran; methanol; water;
DOI:10.1039/c1cc10683j
