2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate

Base Information

• Chemical Name: 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate
• CAS No.: 1095432-84-0
• Molecular Formula: C₁₃H₁₃BrO₆
• Molecular Weight: 345.147
• Mol file: 1095432-84-0.mol

Synonyms:2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate

Chemical Property of 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate

There total 3 articles about 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8) + 4-Bromo-3-methylbenzoic acid methyl ester (148547-19-7) → 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate (1095432-84-0)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; for 1.5h; Cooling with ice; Inert atmosphere;

DOI:10.1039/c1cc10683j

Reference yield: 61.0%

acetic anhydride (108-24-7) + 4-Bromo-3-methylbenzoic acid methyl ester (148547-19-7) → 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate (1095432-84-0)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; acetic acid; at 0 ℃; for 0.5h;

DOI:10.1039/c8cc05174g

Reference yield:

4-bromo-3-methylbenzoic acid (7697-28-1) → 2-bromo-5-(methoxycarbonyl)phenylmethylene diacetate (1095432-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: chromium(VI) oxide; acetic acid; sulfuric acid / 0.5 h / 0 °C

With chromium(VI) oxide; sulfuric acid; acetic acid;

DOI:10.1039/c8cc05174g

upstream raw materials:

acetic anhydride

4-Bromo-3-methylbenzoic acid methyl ester

acetic acid

4-bromo-3-methylbenzoic acid

Downstream raw materials:

4-bromo-3-formyl-benzoic acid methyl ester

3-formyl-4-vinylbenzoic acid methyl ester

3-oxo-indan-5-carboxylic acid methyl ester

4-bromo-3-formyl-benzoic acid