(2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Base Information

Chemical Name:(2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate
CAS No.:223693-15-0
Molecular Formula:C₂₂H₃₆O₅
Molecular Weight:380.525
Hs Code.:

Synonyms:(2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Suppliers and Price of (2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

There total 6 articles about (2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 223693-14-9
(2R,4R)-6-(tert-butyldiphenylsiloxy)-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

: 223693-15-0
(2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran;
DOI:10.1021/ja990384x

Reference yield:

: 3282-30-2
pivaloyl chloride

: 223693-15-0
(2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / pyridine / CH₂Cl₂ / 25 °C

2: 81 percent / triflic acid / diethyl ether / 1 h / 20 °C

3: 94 percent / TBAF / tetrahydrofuran / 72 h

With pyridine; trifluorormethanesulfonic acid; tetrabutyl ammonium fluoride; In tetrahydrofuran; diethyl ether; dichloromethane; 1: Esterification / 2: benzylation / 3: desilylation;
DOI:10.1021/ja993487o

Reference yield:

: 223693-13-8
(2R,4R)-6-(tert-Butyl-diphenyl-silanyloxy)-2,5,5-trimethyl-hexane-1,4-diol

: 223693-15-0
(2R,4R)-6-hydroxy-4-[(p-methoxybenzyl)oxy]-2,5,5-trimethylhexyl pivalate

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / pyridine / CH₂Cl₂ / 25 °C

2: 81 percent / triflic acid / diethyl ether / 1 h / 20 °C

3: 94 percent / TBAF / tetrahydrofuran / 72 h

With pyridine; trifluorormethanesulfonic acid; tetrabutyl ammonium fluoride; In tetrahydrofuran; diethyl ether; dichloromethane; 1: Esterification / 2: benzylation / 3: desilylation;
DOI:10.1021/ja993487o