1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one

Base Information

Chemical Name:1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one
CAS No.:15753-55-6
Molecular Formula:C₁₄H₁₂N₂O
Molecular Weight:224.262
Hs Code.:
DSSTox Substance ID:DTXSID001257575

Synonyms:CDS1_004484;CBMicro_030148;DivK1c_005524;DTXSID001257575;1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one;15753-55-6

Suppliers and Price of 1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:224.094963011
Heavy Atom Count:17
Complexity:269

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C=CNC2=CC=CC=N2

Technology Process of 1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one

There total 9 articles about 1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 504-29-0
2-aminopyridine

: 768-03-6,26742-84-7
Phenyl vinyl ketone

: 15753-55-6
(Z)-1-phenyl-3-(pyridin-2-ylamino)prop-2-en-1-one

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; tert.-butylhydroperoxide; iron(III) chloride; lithium carbonate; In toluene; at 100 ℃; stereoselective reaction;
DOI:10.1039/c9ob01137d

Reference yield: 72.0%

: 504-29-0
2-aminopyridine

: 93-55-0
1-phenyl-propan-1-one

: 15753-55-6
(E)-1-phenyl-3-(pyridin-2-ylamino)prop-2-en-1-one

Guidance literature:: With copper(I) oxide; tert.-butylhydroperoxide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In toluene; at 100 ℃; for 12h; under 760.051 Torr; Reagent/catalyst; Solvent; Temperature; Schlenk technique;
DOI:10.1002/adsc.201900419

Reference yield: 70.0%

: 504-29-0
2-aminopyridine

: 93-55-0
1-phenyl-propan-1-one

: 15753-55-6
(Z)-1-phenyl-3-(pyridin-2-ylamino)prop-2-en-1-one

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; tert.-butylhydroperoxide; iron(III) chloride; lithium carbonate; In toluene; at 100 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; stereoselective reaction; Catalytic behavior;
DOI:10.1039/c9ob01137d