L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Base Information

Chemical Name:L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]
CAS No.:939798-77-3
Molecular Formula:C₂₅H₃₀N₂O₈S₂
Molecular Weight:550.654
Hs Code.:

Synonyms:L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Suppliers and Price of L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

There total 4 articles about L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 939798-78-4
L-(+)-1,1'-methylenebis[5-hydroxymethyl-2-pyrrolidinone]

: 98-59-9
p-toluenesulfonyl chloride

: 939798-77-3
L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;
DOI:10.1016/j.tetasy.2007.02.014

Reference yield:

: 98-79-3
L-Pyroglutamic acid

: 939798-77-3
L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Guidance literature:: Multi-step reaction with 4 steps

1.1: 95 percent / 3 h / 180 °C

2.1: 83 percent / p-TsOH / 16 h / Heating

3.1: sodium borohydride / ethanol; H₂O / 12 h

3.2: 99 percent / ethanol; H₂O; acetone / 0 °C

4.1: 61 percent / NaH / dimethylformamide / 0 °C

With sodium tetrahydroborate; sodium hydride; toluene-4-sulfonic acid; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2007.02.014

Reference yield:

: 16473-66-8
L-(+)-1,1'-methylenebis[5-oxo-2-pyrrolidinecarboxylic acid]

: 939798-77-3
L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester]

Guidance literature:: Multi-step reaction with 3 steps

1.1: 83 percent / p-TsOH / 16 h / Heating

2.1: sodium borohydride / ethanol; H₂O / 12 h

2.2: 99 percent / ethanol; H₂O; acetone / 0 °C

3.1: 61 percent / NaH / dimethylformamide / 0 °C

With sodium tetrahydroborate; sodium hydride; toluene-4-sulfonic acid; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2007.02.014