16473-66-8

Usage

General Description

1,1'-methylenebis(5-L-oxoproline) is a chemical compound also known as MOP. It is a cyclic dipeptide derivative of proline and has been shown to possess antioxidant, anti-inflammatory, and anti-tumor properties. MOP has also been found to inhibit the growth of cancer cells, making it a potential candidate for cancer therapy. Additionally, MOP has been studied for its potential neuroprotective effects and has shown promise in the treatment of neurodegenerative diseases. Overall, MOP is a compound with diverse biological activities and potential therapeutic applications.

Upstream product

• 50-00-0 formaldehyd 
• 56-86-0 L-glutamic acid 
• 109-87-5 Dimethoxymethane 
• 98-79-3 L-Pyroglutamic acid 
• 110-88-3 1,3,5-Trioxan 
• 98-79-3 2-L-pyrrolidone-5-carboxylic acid 
• 56-86-0 acide L(+)glutamique 

Downstream Products

• 7309-47-9 bis(N-pyrrolidinyl)methane 
• 939798-77-3 L-(+)-1,1'-methylenebis[toluene-4-sulfonic asid (S)-5-oxo-pyrrolidin-2-ylmethyl ester] 
• 77269-11-5 L methylene bis N-(oxo-5 pyrrolidine carboxylate-2 de methyle) 

Relevant academic research and scientific papers

An optimised synthetic approach to a chiral derivatising agent and the utilisation of a dimerisation reaction in the synthesis of a novel C2-symmetric diphosphine ligand

We report an optimised synthetic approach to the chiral derivatising agent (5R)-methyl-1-(chloromethyl)-2-pyrrolidinone. In addition, the observation of an unwanted dimerisation product is turned to our advantage by providing a method for the synthesis of a new class of C2-symmetric chiral diphosphine.

Etude dans la serie des pyrrolidinones. IV. Formation de quelques derives de l'acide L methylene bis N-(oxo-5 pyrrolidine carboxylique-2)

Starting from the readily available 5-oxo-2-carboxypyrrolidine, methylene-bis-(N-5-oxo-2-carboxypyrrolidine) was prepared and transformed into a diamine, then into two isomeric diols, which cyclised into one ether.The meso configuration has been assigned for this ether.The reduction of both diols and ether was complete and gave rise to methylene-bis-N-pyrrolidine.