methyl onate

Base Information

• Chemical Name: methyl onate
• CAS No.: 134699-90-4
• Molecular Formula: C₂₉H₃₃N₅O₉S
• Molecular Weight: 627.675
• Mol file: 134699-90-4.mol

Synonyms:methyl onate

Chemical Property of methyl onate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl onate

There total 3 articles about methyl onate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

S,S-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate (32276-00-9) + (2S,4S,5R,6R)-5-Acetylamino-4-benzoyloxy-6-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2-hydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester (134699-89-1) → methyl onate (134699-90-4)

Guidance literature:

With dmap; In acetonitrile;

DOI:10.1248/cpb.39.817

Reference yield:

methyl 5-acetamido, 3,5-dideoxy-8,9-O-isopropylidene-Dglycero-β-D-galacto-2-nonulopyranosonate (114857-70-4) → methyl onate (134699-90-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / pyridine

2: 75 percent / 4-N,N-dimethylaminopyridine / acetonitrile

With pyridine; dmap; In acetonitrile;

DOI:10.1248/cpb.39.817

Reference yield:

benzoic acid anhydride (93-97-0) → methyl onate (134699-90-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / pyridine

2: 75 percent / 4-N,N-dimethylaminopyridine / acetonitrile

With pyridine; dmap; In acetonitrile;

DOI:10.1248/cpb.39.817

upstream raw materials:

S,S-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate

(2S,4S,5R,6R)-5-Acetylamino-4-benzoyloxy-6-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2-hydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester

methyl 5-acetamido, 3,5-dideoxy-8,9-O-isopropylidene-Dglycero-β-D-galacto-2-nonulopyranosonate

benzoic acid anhydride

Downstream raw materials:

methyl 5-acetamido-2,6-anhydro-4-O-benzoyl-3,5-dideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate

methyl (5-acetamido-2,7-anhydro-4-O-benzoyl-3,5-dideoxy-8,9-isopropylidene-α-D-glycero-D-galacto-2-nonulopyranosid)onate

2,7-anhydro-N-acetylneuraminic acid