2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride

Base Information

Chemical Name:2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride
CAS No.:76536-65-7
Molecular Formula:C₂₃H₂₅N₃O₃*ClH
Molecular Weight:427.931
Hs Code.:
DSSTox Substance ID:DTXSID10997891
ChEMBL ID:CHEMBL1743838
Mol file:76536-65-7.mol

Synonyms:76536-65-7;2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride;4H-Pyrimido(6,1-a)isoquinolin-4-one, 6,7-dihydro-9,10-dimethoxy-2-((2,4,6-trimethylphenyl)amino)-, hydrochloride, hydrate (1:1:2);CHEMBL1743838;SCHEMBL10921940;DTXSID10997891;LS-136199;9,10-Dimethoxy-2-[(2,4,6-trimethylphenyl)imino]-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-4-ol--hydrogen chloride (1/1)

Suppliers and Price of 2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-((2,4,6-TRIMETHYLPHENYL)AMINO)-6,7-DIHYDRO-9,10-DIMETHOXY-4H-PYRIMIDO-(6,1-A)ISOQUINOLIN-4-ONE HYDROCHLORIDE DIHYDRATE 95.00%
5MG
$ 499.98

Total 0 raw suppliers

Chemical Property of 2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride

Chemical Property:

Vapor Pressure:1.54E-12mmHg at 25°C
Boiling Point:559.2°C at 760 mmHg
Flash Point:292°C
PSA：65.38000
LogP:5.02740
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:427.1662694
Heavy Atom Count:30
Complexity:679

Purity/Quality:: 2-((2,4,6-TRIMETHYLPHENYL)AMINO)-6,7-DIHYDRO-9,10-DIMETHOXY-4H-PYRIMIDO-(6,1-A)ISOQUINOLIN-4-ONE HYDROCHLORIDE DIHYDRATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C)NC2=NC(=O)N3CCC4=CC(=C(C=C4C3=C2)OC)OC)C.Cl

Technology Process of 2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride

There total 2 articles about 2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 75535-96-5
2-Chloro-9,10-dimethoxy-6,7-dihydro-4H-pyrimido(6,1-a)isoquinolin-4-one

: 88-05-1
2,4,6-trimethylaniline

: 76536-65-7
9,10-dimethoxy-2-(mesitylamino)-6,7-dihydro-4H-pyrimido<6,1-a>isoquinolin-4-one hydrochloride

Guidance literature:: In chloroform; for 20h; Heating;
DOI:10.1002/hlca.19860690722

Reference yield:

: 75535-95-4
1-<2-(3,4-Dimethoxyphenyl)ethyl>pyrimidin-2,4,6(1H,3H,5H)-trion

: 76536-65-7
9,10-dimethoxy-2-(mesitylamino)-6,7-dihydro-4H-pyrimido<6,1-a>isoquinolin-4-one hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / POCl₃ / 24 h / 80 °C

2: 90 percent / CHCl₃ / 20 h / Heating

With trichlorophosphate; In chloroform;
DOI:10.1002/hlca.19860690722