1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Base Information

Chemical Name:1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea
CAS No.:1337932-25-8
Molecular Formula:C₁₅H₁₈Cl₂N₆O₂
Molecular Weight:385.253
Hs Code.:

Synonyms:1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Suppliers and Price of 1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

There total 3 articles about 1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1337932-35-0
N,N-diphenoxycarbonyl-6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-amine

: 108-00-9
N,N-dimethylethylenediamine

: 1337932-25-8
1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃; for 20h; Inert atmosphere;

Reference yield:

: 36556-51-1
2,3-dichloro-1-fluoro-4-nitrobenzene

: 1337932-25-8
1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 1.5 h / 20 °C

1.2: 16 h

2.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

2.2: 1.5 h / 60 °C

3.1: tetrahydrofuran / 20 h / 0 - 20 °C / Inert atmosphere

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide;

Reference yield:

: 1337932-19-0
6-(2,3-dichloro-4-nitrophenoxy)pyrimidin-4-amine

: 1337932-25-8
1-(6-(4-amino-2,3-dichlorophenoxy)pyrimidin-4-yl)-3-(2-(dimethyl amino)ethyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

1.2: 1.5 h / 60 °C

2.1: tetrahydrofuran / 20 h / 0 - 20 °C / Inert atmosphere

With triethylamine; In tetrahydrofuran; dichloromethane;