C₂₀H₁₈F₃N₃

Base Information

Chemical Name:C₂₀H₁₈F₃N₃
CAS No.:1353554-90-1
Molecular Formula:C₂₀H₁₈F₃N₃
Molecular Weight:357.378
Hs Code.:

C<sub>20</sub>H<sub>18</sub>F<sub>3</sub>N<sub>3</sub>

Synonyms:C₂₀H₁₈F₃N₃

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Chemical Property of C₂₀H₁₈F₃N₃

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Technology Process of C₂₀H₁₈F₃N₃

There total 4 articles about C₂₀H₁₈F₃N₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1353556-06-5
C₃₀H₃₄F₃N₃O₄

: 1353554-90-1
C₂₀H₁₈F₃N₃

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h; Cooling with ice;

Reference yield:

: 20366-57-8
(5-bromo-naphthalen-1-yl)-methanol

: 1353554-90-1
C₂₀H₁₈F₃N₃

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 100 °C

2: triphenylphosphine; di-isopropyl azodicarboxylate / toluene / 3.25 h / 0 - 20 °C

3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C / Cooling with ice

With di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; trifluoroacetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water; toluene; 1: Suzuki Coupling;

Reference yield:

: 41498-06-0
5-bromo-1-naphthaldehyde

: 1353554-90-1
C₂₀H₁₈F₃N₃

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate / ethanol / 0.5 h / 20 °C

2: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 100 °C

3: triphenylphosphine; di-isopropyl azodicarboxylate / toluene / 3.25 h / 0 - 20 °C

4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C / Cooling with ice

With sodium tetrahydroborate; di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; trifluoroacetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; dichloromethane; water; toluene; 2: Suzuki Coupling;